5-Carbethoxyuracil → HCID 67028868, compound

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The title compound was prepared according to Method B and the experimentals described for compound 92 from 3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride and ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate. M/e+ 425 for C21H18ClN4O4 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 9.72 (s, 1H), 8.32 (d, J=6.9 Hz, 1H), 7.67 (m, 4H), 7.48 (d, J=8.4 Hz, 2H), 7.31 (t, J=7.3 Hz, 1H), 6.93 (t, J=6.96 Hz, 1H), 5.49 (s, 2H), 4.10 (q, J=6.9 Hz, 2H), 1.16 (t, J=6.9 Hz, 3H) ppm.

Provenance & Evidence