Pyrrolidine → HCID 67028630, compound

Participants

Reaction Steps

The title compound was prepared according to the experimental for compound 132 from 4-chloro-1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2(1H)-one and pyrrolidine. M/e+ 406 for C22H21ClN5O (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.44 (d, J=6.6 Hz, 1H), 7.69 (d, J=8.4 Hz, 2H), 7.63 (d, J=8.8 Hz, 1H), 7.47 (d, J=8.4 Hz, 2H), 7.28 (m, 1H), 6.86 (td, J=6.9, 1.1 Hz, 1H), 6.73 (d, J=7.3 Hz, 1H), 5.57 (s, 2H), 5.49 (d, J=7.7 Hz, 1H), 3.65 (t, J=6.6 Hz, 2H), 3.28 (t, J=6.6 Hz, 2H), 1.90 (m, 4H) ppm.

Provenance & Evidence