反应详情

The title compound was prepared according to Method A and the experimentals described for compound 139 from 3-(chloromethyl)-2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridine hydrochloride and 4-chloro-6-methylpyrimidin-2-amine. H-NMR (400 MHz, CDCl3) 8.021 (s, 1H), 7.73 (m, 2H), 7.51 (d, J=9.164 Hz, 1H), 7.10 (m, 2H), 6.50 (s, 1H), 5.28 (broad, 1H, D, NH), 4.98 (d, J=5.032 Ha, 2H, D, CH2), 2.29 (s, 3H, D, CH3), 2.26 (s, 3H) ppm; m/e+ 382.0, 384.1 for C20H17ClFN5 (M+H)+