化工社化工社 化学情報印刷レポート · 研究参考用
2-Amino-4-chloro-6-methylpyrimidine → 4-chloro-N-((6-chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-6-methylpyrimidin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-4-chloro-6-methylpyrimidine | HCID 21810 | — |
| 反応物 | 6-Chloro-3-(chloromethyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyridine hydrochloride | HCID 67028637 | — |
| 生成物 | 4-chloro-N-((6-chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-6-methylpyrimidin-2-amine | HCID 86655122 | — |
反応手順
The title compound was prepared according to Method A and the experimentals described for compound 139 from 6-chloro-3-(chloromethyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyridine hydrochloride and 4-chloro-6-methylpyrimidin-2-amine. m/e+ 402.0, 404.0 for C19H14C12FN5.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08497278B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-572581b9825d480db4faabdaaba8e641 |
| 出典メモ | uspto-grants-2013_07 |