HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → 6-Methyl-3-phenylsulfanylmethyl-2-p-tolyl-imidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | 3-(Chloromethyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridine hydrochloride | HCID 67028724 | — |
| Product | 6-Methyl-3-phenylsulfanylmethyl-2-p-tolyl-imidazo[1,2-a]pyridine | HCID 67027725 | — |
Reaction Steps
The title compound was prepared according to Method A and the experimentals described for compound 139 from 3-(chloromethyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridine hydrochloride and benzenethiol. m/e+ 345 for C22H21N2 (M+H)+; 1H NMR (400 MHz, CDCl3) δ 7.81 (s, 1H), 7.59 (d, J=8.0 Hz, 2H), 7.54 (d, J=9.1 Hz, 1H), 7.35 (d, J=1.8 Hz, 2H), 7.32 (m, 5H), 7.07 (d, J=9.1 Hz, 1H), 4.54 (s, 2H), 2.39 (s, 3H), 2.34 (s, 3H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497278B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-ccd6cb70367e43adb80652e76945b2ae |
| Source note | uspto-grants-2013_07 |