HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-4,6-difluoropyrimidine → 4,6-difluoro-N-((2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Amino-4,6-difluoropyrimidine | HCID 1201480 | — |
| Edukt | 3-(Chloromethyl)-2-phenylimidazo[1,2-a]pyridine hydrochloride | HCID 67028785 | — |
| Produkt | 4,6-difluoro-N-((2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine | HCID 67029082 | 17% |
Reaktionsschritte
The title compound was prepared according to Method A and the experimentals described for compound 139 from 3-(chloromethyl)-2-phenylimidazo[1,2-a]pyridine hydrochloride and 4,6-difluoropyrimidin-2-amine. (0.10 g, 17% yield), M/e− 338.2 for C18H13F2N5 (M+H)+
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08497278B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-16f9e0327caf4022bd770cac06923ce3 |
| Quellennotiz | uspto-grants-2013_07 |