2-Thiophenethiol → HCID 67027626, compound

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Reaction Steps

The title compound was prepared according to Method A and the experimentals described for compound 139 from 3-(chloromethyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridine hydrochloride and thiophene-2-thiol. m/e+ 351 for C20H19N2S2 [M+H]+; 1H-NMR (400 MHz, CDCl3) δ 7.75 (s, 1H), 7.53 (s, 1H), 7.50 (d, J=8.0 Hz, 2H), 7.29 (dd, J=1.1, 5.1 Hz, 1H), 7.20 (d, J=8.0 Hz, 2H), 7.04 (dd, J=1.4, 9.1 Hz, 1H), 6.95 (dd, J=1.1, 3.6 Hz, 1H), 6.87 (dd, J=3.6, 5.5 Hz, 1H), 4.40 (s, 2H), 2.37 (s, 3H), 2.33 (s, 3H) ppm; 13C-NMR (100 MHz, CDCl3, δ) 145.528, 144.436, 137.718, 135.777, 132.167, 131.485, 131.098, 129.437, 128.391, 128.057, 127.944, 122.074, 121.711, 117.032, 114.621, 33.849, 21.527, 18.699 ppm.

Provenance & Evidence