Methylhydrazine → 2-(4-Chlorophenyl)-3-((6-(2-methylhydrazinyl)pyrazin-2-yl)methyl)imidazo[1,2-a]pyridine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Methylhydrazine	HCID 6061	—
Edukt	1-(2-((6-Chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidin-4-yl)-4-methylpiperidin-4-ol	HCID 67029099	—
Edukt	2-(4-Chlorophenyl)-3-((6-chloropyrazin-2-yl)methyl)imidazo[1,2-a]pyridine	HCID 86655124	—
Produkt	2-(4-Chlorophenyl)-3-((6-(2-methylhydrazinyl)pyrazin-2-yl)methyl)imidazo[1,2-a]pyridine	HCID 67027557	—

Reaktionsschritte

The title compound was prepared according to the experimental for compound 187 from 2-(4-chlorophenyl)-3-((6-chloropyrazin-2-yl)methyl)imidazo[1,2-a]pyridine and methylhydrazine. M/e+ 365 for C19H18ClN6 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.41 (s, 1H), 8.12 (d, J=6.9 Hz, 1H), 7.83 (d, J=8.4 Hz, 2H), 7.73 (s, 1H), 7.63 (d, J=9.1 Hz, 1H), 7.41 (d, J=8.4 Hz, 2H), 7.19 (m, 1H), 6.78 (t, J=6.9 Hz, 1H), 4.36 (s, 2H), 3.88 (bs, 2H), 3.18 (s, 3H) ppm.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08497278B2
Quelldatensatz	uspto-grants-2013_07
ORD ID	ord-83efa8abc54a46d8ab4a2e508b40d52b
Quellennotiz	uspto-grants-2013_07