N-Methylethylamine → HCID 67027585, compound

Participants

Reaction Steps

The title compound was prepared in the same fashion as that described for compound 196 from 2-((6-chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidine-4-carbaldehyde and N-methylethanamine. (0.068 g, 40% yield). M/e+ 425.1 for C22H22ClFN6 (M+H)+; 1H-NMR (500 MHz, CDCl3, δ) 8.55 (s, 1H), 8.30 (d, J=5.0 Hz, 1H), 7.78-7.75 (m, 2H), 7.57 (d, J=9.5 Hz, 1H), 7.20-7.15 (m, 3H), 6.83 (d, J=5.0 Hz, 1H), 5.26 (br s, 1H), 5.05 (d, J=6.0 Hz, 2H), 3.48 (s, 2H), 2.51 (q, J=7.0 Hz, 2H), 2.28 (s, 3H), 1.11 (t, J=7.0 Hz, 3H)

Provenance & Evidence