Pyrrolidine → HCID 67027731, compound

Participants

Reaction Steps

The title compound was prepared in the same fashion as that described for compound 196 from 2-((6-chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidine-4-carbaldehyde and pyrrolidine. (0.040 g, 33% yield). M/e+ 437.1 for C23H22ClFN6 (M+H)+; 1H-NMR (500 MHz, CDCl3, δ) 8.54 (s, 1H), 8.30 (d, J=5.0 Hz, 1H), 7.77-7.75 (m, 2H), 7.57 (dd, J=9.5. 0.5 Hz, 1H), 7.20-7.15 (m, 3H), 6.81 (d, J=5.0 Hz, 1H), 5.32-5.26 (m, 1H), 5.05 (d, J=5.5 Hz, 2H), 3.64 (s, 2H), 2.64 (br s, 4H), 1.84 (br s, 4H).

Provenance & Evidence