1H-1,2,4-Triazole, 1-methyl- → 6-fluoro-2-(4-fluorophenyl)-3-((1-methyl-1H-1,2,4-triazol-5-yl)methyl)imidazo[1,2-a]pyridine

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Reaction Steps

The title compound was prepared according to Method C and the experimentals described for compound 199 from 6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde and 1-methyl-1H-1,2,4-triazole. (0.19 g, 53% yield). M/e+ 326.2 for C17H14F2N5 (M+H)+; 1H-NMR (500 MHz, DMSO-d6, δ) 8.55 (dd, J=5.0, 2.0 Hz, 1H), 7.72-7.68 (m, 4H), 7.40-7.36 (m, 1H), 7.31-7.27 (m, 2H), 4.64 (s, 2H), 3.86 (s, 3H).

Provenance & Evidence