Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-1,3,4-oxadiazole → 2-((2-(4-Chlorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)-5-methyl-1,3,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-1,3,4-oxadiazole | HCID 558447 | — |
| 반응물 | 2-(4-Chlorophenyl)-6-methylimidazo[1,2-a]pyridine-3-carbaldehyde | HCID 2757806 | — |
| 반응물 | 6-fluoro-2-(4-fluorophenyl)-3-((1-methyl-1H-imidazol-2-yl)methyl)imidazo[1,2-a]pyridine | HCID 67029064 | — |
| 생성물 | 2-((2-(4-Chlorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)-5-methyl-1,3,4-oxadiazole | HCID 67027492 | — |
반응 단계
The title compound was prepared according to Method C and the experimentals described for compound 199 from 2-(4-chlorophenyl)-6-methylimidazo[1,2-a]pyridine-3-carbaldehyde and 2-methyl-1,3,4-oxadiazole. M/e+ 339 for C18H16ClN4O (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 7.95 (s, 1H), 7.76 (d, J=8.4 Hz, 2H), 7.56 (d, J=9.1 Hz, 1H), 7.45 (d, J=8.4 Hz, 2H), 7.10 (dd, J=9.1, 1.4 Hz, 1H), 4.54 (s, 2H), 2.49 (s, 3H), 2.35 (s, 3H) ppm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08497278B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-01079419ffa9439db91c9810754c18a5 |
| 출처 메모 | uspto-grants-2013_07 |