HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-1,3,4-oxadiazole → 2-((2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-5-methyl-1,3,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-1,3,4-oxadiazole | HCID 558447 | — |
| Reactant | 2-(4-Chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde | HCID 2757793 | — |
| Reactant | 6-fluoro-2-(4-fluorophenyl)-3-((1-methyl-1H-imidazol-2-yl)methyl)imidazo[1,2-a]pyridine | HCID 67029064 | — |
| Product | 2-((2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-5-methyl-1,3,4-oxadiazole | HCID 67028791 | — |
Reaction Steps
The title compound was prepared according to Method C and the experimentals described for compound 199 from 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde and 2-methyl-1,3,4-oxadiazole. M/e+ 325 for C17H14ClN4O (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.22 (d, J=6.6 Hz, 1H), 7.80 (d, J=8.4 Hz, 2H), 7.67 (d, J=9.1 Hz, 1H), 7.47 (d, J=8.4 Hz, 2H), 7.27 (t, J=6.9 Hz, 1H), 6.91 (d, J=6.6 Hz, 1H), 4.58 (s, 2H), 2.50 (s, 3H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497278B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-234c3edc7b3d4e87be8758fda64ff2a4 |
| Source note | uspto-grants-2013_07 |