Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Vinylimidazole → 2-(4-chlorophenyl)-3-((1-vinyl-1H-imidazol-2-yl)methyl)imidazo[1,2-a]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Vinylimidazole | HCID 66171 | — |
| 반응물 | 2-(4-Chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde | HCID 2757793 | — |
| 반응물 | 6-fluoro-2-(4-fluorophenyl)-3-((1-methyl-1H-imidazol-2-yl)methyl)imidazo[1,2-a]pyridine | HCID 67029064 | — |
| 생성물 | 2-(4-chlorophenyl)-3-((1-vinyl-1H-imidazol-2-yl)methyl)imidazo[1,2-a]pyridine | HCID 67028933 | — |
반응 단계
The title compound was prepared according to Method C and the experimentals described for compound 199 from 2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde and 1-vinyl-1H-imidazole. (34 mg, 18%). m/e+=335 (M+H+). 1H-NMR (400 MHz, CDCl3, δ): 8.28 (d, 1H, D, J=7.0 Hz), 7.66 (d, 2H, D, J=10.2 Hz), 7.61 (d, 1H, D, J=9.2 Hz), 7.46 (d, 2H, D, J=8.5 Hz), 7.19 (t, 1H, D, J=7.9 Hz), 7.08 (d, 1H), 6.96 (d, 1H), 6.80 (t, 1H, D, J=7.0 Hz), 6.46 (m, 1H), 5.03 (m, 1H), 4.62 (m, 1H), 4.56 (s, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08497278B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-bd0adb78bd4140ecbb4124bda0ccbd24 |
| 출처 메모 | uspto-grants-2013_07 |