2-(4-chlorophenyl)-3-((1-vinyl-1H-1,2,4-triazol-5-yl)methyl)imidazo[1,2-a]pyridine → 3-((1H-1,2,4-triazol-5-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

HRID 455130Notes

Reaction equation

HRID 455130 reaction equation
N1C(CC2N3C=C(F)C=CC3=NC=2C2C=CC(F)=CC=2)=NC=N1.[Cl:24][C:25]1[CH:30]=[CH:29][C:28]([C:31]2[N:32]=[C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][N:34]3[C:39]=2[CH2:40][C:41]2[N:45](C=C)[N:44]=[CH:43][N:42]=2)=[CH:27][CH:26]=1>>[NH:45]1[C:41]([CH2:40][C:39]2[N:34]3[CH:35]=[CH:36][CH:37]=[CH:38][C:33]3=[N:32][C:31]=2[C:28]2[CH:29]=[CH:30][C:25]([Cl:24])=[CH:26][CH:27]=2)=[N:42][CH:43]=[N:44]1

Participants

3

Reactant 2

HCID 670287712-(4-chlorophenyl)-3-((1-vinyl-1H-1,2,4-triazol-5-yl)methyl)imidazo[1,2-a]pyridineHCID 670290043-((1H-1,2,4-triazol-5-yl)methyl)-6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridine

Product 1

HCID 670288133-((1H-1,2,4-triazol-5-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

Procedure

The title compound was prepared according to the experimentals described for compound 210 from 2-(4-chlorophenyl)-3-((1-vinyl-1H-1,2,4-triazol-5-yl)methyl)imidazo[1,2-a]pyridine. m/e+ 310 for C16H13ClN5 (M+H)+.

Sources & evidence

ORD record
ord-8246fb4644c6429d9e7ea3a5661e742f
Source dataset
uspto-grants-2013_07
Patent number
US08497278B2

Reaction notes

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