Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 455151Generated: October 30, 2026

1-Methylpiperazine → HCID 67028932, compound

https://huagongshe.com/reaction/455151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
ReactantHCID 67028741HCID 67028741—
ReactantHCID 67029115HCID 67029115—
ProductHCID 67028932HCID 67028932—

Reaction Steps

The title compound was prepared according to the experimental for compound 237 from 1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-4-methoxy-1H-pyrrol-2(5H)-one and 1-methylpiperazine. (56 mg, 47%) m/e+=422 (M+H+). 1H-NMR (400 MHz, CDCl3, δ): 8.47 (d, 1H, D, J=7.0 Hz), 7.73 (d, 2H, D, J=8.4 Hz), 7.62 (d, 1H, D, J=9.1 Hz), 7.47 (d, 2H, D, J=8.4 Hz), 7.25 (t, 1H, D, J=7.3 Hz), 6.85 (t, 1H, D, J=6.4 Hz), 5.09 (s, 2H), 4.74 (s, 1H), 3.57 (s, 2H), 3.03 (m, 4H), 2.36 (m, 4H), 2.27 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497278B2
Source datasetuspto-grants-2013_07
ORD IDord-3c03067cc0db4a7a98af5307215f2271
Source noteuspto-grants-2013_07