4-Hydroxypyrrolidine → HCID 67028885, compound

Participants

Reaction Steps

The title compound was prepared according to the experimental for compound 237 from 1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-4-methoxy-1H-pyrrol-2(5H)-one and pyrrolidin-3-ol. (33 mg, 32%) m/e+=409 (M+H+). 1H-NMR (400 MHz, CDCl3, δ): 8.46 (d, 1H, D, J=7.0 Hz), 7.73 (d, 2H, D, J=8.4 Hz), 7.61 (d, 1H, D, J=9.1 Hz), 7.46 (d, 2H, D, J=8.4 Hz), 7.25 (t, 1H, D, J=7.3 Hz), 6.84 (t, 1H, D, J=7.3 Hz), 5.09 (s, 2H), 4.57 (s, 1H), 4.53 (m, 1H), 3.55 (s, 2H), 3.2 (m, 4H), 2.1 (m, 3H).

Provenance & Evidence