HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl pyridine-3,5-dicarboxylate → Dimethyl piperidine-3,5-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl pyridine-3,5-dicarboxylate | HCID 78339 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Dimethyl piperidine-3,5-dicarboxylate | HCID 49761012 | — |
Reaction Steps
Pyridine-3,5-dicarboxylic acid dimethyl ester (5.3 g, 27 mmol) and Rh/PtO2 (0.5 g) in MeOH (200 mL) are stirred under hydrogen overnight. The resulting mixture is filtered and the solvents are evaporated to give a brown oil. MS (LC-MS): 202 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497286B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-080a5bb57e19404f996977073d5869eb |
| Source note | uspto-grants-2013_07 |