HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 6,6-Dimethyl-5,6-dihydro-benzo[f]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 4,4-Dimethyl-1,2,3,4-tetrahydronaphthalen-2-one | HCID 12772843 | — |
| Product | 6,6-Dimethyl-5,6-dihydro-benzo[f]quinoline | HCID 58294616 | 49% |
Reaction Steps
The title compound is prepared from 4,4-dimethyl-3,4-dihydro-1H-naphthalen-2-one and propargylamine following a procedure analogous to that described in Step 1 of Intermediates 1 and 2. Yield: 49% of theory; LC (method 1): tR=2.40 min; Mass spectrum (ESI+): m/z=210 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497281B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-8df42d2770f04a349063acc1bafc5270 |
| Source note | uspto-grants-2013_07 |