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HRID45537

反应详情

EQUATION

反应方程式

HRID 45537 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cn[nH]c2)OC1(C)C
HCID2774010

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

C9H15BN2O2

结构：Brc1ccc(C(CCn2ccnc2)Oc2ccccc2)cc1
HCID59331953

1-[3-(4-Bromophenyl)-3-phenoxypropyl]-1H-imidazole

C18H17BrN2O

PRODUCTS

生成物

1
结构：c1ccc(OC(CCn2ccnc2)c2ccc(-c3cn[nH]c3)cc2)cc1
HCID11348499

4-[4-(3-Imidazol-1-yl-1-phenoxy-propyl)-phenyl]-1H-pyrazole

C21H20N4O

PROCEDURE

实验过程

1-[3-(4-Bromo-phenyl)-3-phenoxy-propyl]-1H-imidazole was reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole following the procedure set out in Example 1 to give the title compound. LC/MS: (PS-A2) Rt 2.05 [M+H]+ 345.30. 1H NMR (Me-d3-OD) δ 2.30-2.55 (2H, m), 4.25-4.45 (2H, m), 5.10-5.15 (1H, m), 6.80-6.90 (3H, m), 7.10 (1H, s), 7.15-7.20 (2H, t), 7.25 (1H, s), 7.35-7.40 (2H, d), 7.55-7.60 (2H, d), 7.85 (1H, s), 7.95 (2H, s).