cis-6-Methoxy-5-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine → HCID 178487190, compound

HRID 455377Notes

Reaction equation

HRID 455377 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:13][O:14][C:15]1[CH:16]=[CH:17][C:18]2[CH2:19][C@H:20]3[C@@H:25]([C:26]=2[C:27]=1[CH3:28])[CH2:24][CH2:23][CH2:22][NH:21]3>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:21]3[CH2:22][CH2:23][CH2:24][C@@H:25]4[C:26]5[C:27]([CH3:28])=[C:15]([O:14][CH3:13])[CH:16]=[CH:17][C:18]=5[CH2:19][C@H:20]34)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 67222612cis-6-Methoxy-5-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridineHCID 178524171HCID 178524171, compound

Product 1

HCID 178487190HCID 178487190, compound

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-6-methoxy-5-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine following a procedure analogous to that described in Example 1.

Sources & evidence

ORD record
ord-3d63f5504e074a17a4788421596de5ed
Source dataset
uspto-grants-2013_07
Patent number
US08497281B2

Reaction notes

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