HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67194742, compound → HCID 178519367, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67194742 | HCID 67194742 | — |
| Reactant | HCID 178524171 | HCID 178524171 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 178519367 | HCID 178519367 | 70% |
Reaction Steps
The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and trans-7,9-difluoro-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1. Yield: 70% of theory; TLC: rf=0.43 (silica gel, CH2Cl2/MeOH/32% aqueous NH3 90:10:1); Mass spectrum (ESI+): m/z=368 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497281B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-6dfdfd139cf64dedbeec79cd699d7f36 |
| Source note | uspto-grants-2013_07 |