HCID 131730736, compound → HCID 131730737, compound

Participants

Reaction Steps

A solution of 4-[1,5-bis-(tert-butyl-dimethyl-silanyloxymethyl)-8-oxa-bicyclo[3.2.1]octa-2,6-dien-3-yl]-phenylamine (as prepared in the previous step, 500 mg, 1.03 mmol) and 5% Rh/Al2O3 (250 mg, 50 wt %) in 20 mL of MeOH was stirred at RT under H2 (balloon pressure) for 2 h. The Rh catalyst was removed by filtration on Celite, and the filtrate was concentrated in vacuo to give 500 mg of the 4-[1,5-bis-(tert-butyl-dimethyl-silanyloxymethyl)-8-oxa-bicyclo[3.2.1]oct-2-en-3-yl]-phenylamine as a light brown oil Mass spectrum (ESI, m/z): Calcd. for C27H47NO3Si2, 490.3 (M+H), found 490.1.

Provenance & Evidence