HCID 131730735, compound → HCID 131730738, compound

Participants

Reaction Steps

A mixture of 1,5-bis-(tert-butyl-dimethyl-silanyloxymethyl)-8-oxa-bicyclo[3.2.1]-oct-6-en-3-one (200 mg, 4.84 mmol)(Lee, K. and Cha, J. K., J. Amer. Chem. Soc., 123:5590-5591 (2001)) and 5% Pd/C (30 mg) in 10 mL of MeOH was stirred at RT under H2 (balloon pressure) for 8 h. The Pd catalyst was removed by filtration on Celite, and the filtrate was concentrated to give 200 mg (100%) of the title compound as a colorless oil. Mass spectrum (ESI, m/z): Calcd. for C21H42O4Si2, 415.2 (M+H), found 415.1.

Provenance & Evidence