4'-Chloro-4-biphenylol → 2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester

Participants

Reaction Steps

By an operation similar to that in Example 2-1 and using 2-{[4-(chloroacetyl)-1,3-thiazol-2-yl]thio}-2-methylpropionic acid tert-butyl ester (561 mg) obtained in Example 1 and 4′-chlorobiphenyl-4-ol (307 mg), 2-[(4-{[(4′-chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester (129 mg) was obtained. Furthermore, by operations similar to those in Example 2-2 and 2-3, the title compound (36 mg) was obtained.

Provenance & Evidence