HRID456075

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID303862

2-hydrazino-1,3-benzoxazole

C7H7N3O

结构：CC(=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1

HCID58190599

未命名化合物

PRODUCTS

生成物

$结构：C/C(=N\Nc1nc2ccccc2o1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1$

HCID71699876

未命名化合物

收率 74%

PROCEDURE

实验过程

The title compound was prepared from 2-hydrazinylbenzo[d]oxazole and 1-[3-(7-fluoro-quinolin-6-ylmethyl)-imidazo[1,2-b]pyridazin-6-yl]-ethanone in analogy to the synthesis of example 1 in 74% yield. 1H-NMR (400 MHz, DMSO-d6) δ ppm 11.8-11.5 (m, 1H), 8.87 (dd, 1H), 8.4-7.9 (m, 4), 7.8-7.6 (m, 2H), 7.6-7.1 (m, 5H), 4.58 (s, 2H), 2.49 (s, 3H). LCMS (method C): [MH]+=452, tR=4.42 min.