HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonohydrazide → N-[(E)-1-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]ethylideneamino]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonohydrazide | HCID 269268 | — |
| Reactant | 1-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanone | HCID 59341802 | — |
| Product | N-[(E)-1-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]ethylideneamino]methanesulfonamide | HCID 71699915 | — |
Reaction Steps
The title compound was prepared in analogy to the synthesis of example 52 from 1-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanone and methanesulfono-hydrazide. 1H-NMR (400 MHz, DMSO-d6) δ ppm 9.45 (s, 1H), 8.89 (m, 1H), 8.36 (d, 1H), 7.82 (m, 2H), 7.85 (dd, 1H), 7.53 (dd, 1H), 6.21 (s, 2H), 3.20 (s, 3H), 2.35 (s, 3H)). LCMS (method B): [MH]+=446, tR=1.37 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497368B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-044b153931854c7f993147fe03e3e8f5 |
| Source note | uspto-grants-2013_07 |