1-Amino-1-methylurea → 1-methyl-1-[(E)-1-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]ethylideneamino]urea

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Reaction Steps

The title compound was prepared as a white solid in analogy to the synthesis of example 52 from 1-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)ethanone and 1-methylhydrazine-carboxamide. 1H-NMR (400 MHz, DMSO-d6) δ ppm 9.68 (s, 1H), 8.89 (m, 1H), 8.36 (d, 1H), 8.03 (s, 1H), 8.01 (d, 1H), 7.82 (dd, 1H), 7.53 (dd, 1H), 6.75 (s, 2H), 6.21 (s, 2H) 2.50 (s, 3H), 2.49 (s, 3H). LCMS (method B): [MH]+=376, tR=1.88 min.

Provenance & Evidence