4-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)- → HCID 58120069, compound

HRID 456201Notes

Reaction equation

HRID 456201 reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:3]=1[CH2:4]Br.[CH3:12][C@H:13]1[C@@H:17]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[O:16][C:15](=[O:24])[NH:14]1>>[Br:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:3]=1[CH2:4][N:14]1[C@@H:13]([CH3:12])[C@@H:17]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[O:16][C:15]1=[O:24]

Participants

3

Reactant 2

HCID 8531614-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)-HCID 35259512-Bromo-5-methoxybenzyl bromide

Product 1

HCID 58120069HCID 58120069, compound

Procedure

Prepared according to the procedure described in Example 1, Step 3, using the following starting materials: 2-bromo-5-methoxybenzyl bromide and (4S,5R)-(−)-4-methyl-5-phenyl-2-oxazolidinone.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-72c2ce357df34fddb16e97072efbf91a
Source dataset
uspto-grants-2013_07
Patent number
US08497381B2

Reaction notes

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