HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-methoxyphenylacetic acid → [4-Methoxy-2'-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-methoxyphenylacetic acid | HCID 555306 | — |
| Reactant | (4S,5R)-4-Methyl-5-phenyl-3-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-oxazolidin-2-one | HCID 66890959 | — |
| Product | [4-Methoxy-2'-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid | HCID 44205722 | — |
Reaction Steps
Prepared according to the procedure described in Example 7, Step 2, using the following starting materials: (4S,5R)-4-methyl-5-phenyl-3-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-oxazolidin-2-one and 5-bromo-2-methoxyphenylacetic acid. M+H is 500.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497381B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-fd689a3f5e57491ab3a99985a2eb3ab5 |
| Source note | uspto-grants-2013_07 |