3-Pyridinylboronic acid → HCID 44206168, compound

HRID 456228Notes

Reaction equation

HRID 456228 reaction equation
C[O:2][C:3](=[O:43])[CH2:4][C:5]1[CH:6]=[C:7]([C:19]2[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][C:20]=2[CH2:29][N:30]2[C@@H:34]([CH3:35])[C@@H:33]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)[O:32][C:31]2=[O:42])[C:8](OS(C(F)(F)F)(=O)=O)=[CH:9][CH:10]=1.[N:44]1[CH:49]=[CH:48][CH:47]=[C:46](B(O)O)[CH:45]=1>>[CH3:35][C@H:34]1[C@@H:33]([C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=2)[O:32][C:31](=[O:42])[N:30]1[CH2:29][C:20]1[CH:21]=[C:22]([C:25]([F:27])([F:26])[F:28])[CH:23]=[CH:24][C:19]=1[C:7]1[C:8]([C:46]2[CH:45]=[N:44][CH:49]=[CH:48][CH:47]=2)=[CH:9][CH:10]=[C:5]([CH2:4][C:3]([OH:2])=[O:43])[CH:6]=1

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 86650343HCID 86650343, compound

Product 1

HCID 44206168HCID 44206168, compound

Procedure

Prepared according to the procedure described in Example 19, Step 3, using the following starting materials: [2′-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-6-trifluoromethanesulfonyloxy-4′-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester and 3-pyridineboronic acid. M+H is 547.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-45a2ac8275784a05925983e7420f26a2
Source dataset
uspto-grants-2013_07
Patent number
US08497381B2

Reaction notes

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