Hydrochloric Acid → HCID 66891008, compound

Participants

Reaction Steps

To [6-methoxy-2′-((3aR,8aS)-2-oxo-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-3-ylmethyl)-4′-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester (0.091 g, 0.18 mmol) in THF (0.9 mL) and MeOH (0.7 mL) was added IN aqueous NaOH (0.45 mL), and the reaction was stirred at room temperature for 2 hours. The mixture was acidified with 1N aqueous HCl and extracted with CH2Cl2. The combined organic layers were washed with H2O, dried over MgSO4, filtered, and concentrated to give the title compound. M+H is 498.

Provenance & Evidence