HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → N-{4-[2-(3-Methoxyphenyl)ethoxy]benzoyl}glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | 3-Methoxyphenethyl alcohol | HCID 78724 | — |
| Reactant | N-[4-(2-Cyclopropylethoxy)benzoyl]glycine | HCID 66812105 | — |
| Product | N-{4-[2-(3-Methoxyphenyl)ethoxy]benzoyl}glycine | HCID 66811982 | 92% |
Reaction Steps
The same reactions as in Example 9 (9a) and (9b) were conducted using methyl 4-hydroxybenzoate (4.26 g, 28.0 mmol) and 2-(3-methoxyphenyl)ethanol (4.32 mL, 31.0 mmol) to give 8.54 g of the title compound (colorless crystal, yield: 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497397B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-921bdd4e8bc84b2f9e42608c528629f5 |
| Source note | uspto-grants-2013_07 |