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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456309Generated: October 30, 2026

4-(2-Hydroxyethyl)benzonitrile → HCID 66812162, compound

https://huagongshe.com/reaction/456309

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Hydroxyethyl)benzonitrileHCID 2800815—
ReactantN-(4-Hydroxybenzoyl)glycine tert-butyl esterHCID 10682169—
ProductHCID 66812162HCID 6681216246%

Reaction Steps

The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (582 mg, 3.83 mmol) prepared in Example 1 (1a) and 4-(2-hydroxyethyl)benzonitrile (592 mg, 4.02 mmol) to give 226 mg of the title compound (white powder, yield: 46%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497397B2
Source datasetuspto-grants-2013_07
ORD IDord-81cedcb213d4425393cb30bda78508ed
Source noteuspto-grants-2013_07