Sodium Hydroxide → HCID 178443202, compound

HRID 456380Notes

Reaction equation

HRID 456380 reaction equation
[P:1]([O-:21])([O-:20])([O:3][CH:4]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH2:5][CH2:6][CH3:7])=[O:2].[OH-].[Na+:23]>C(O)C>[P:1]([OH:21])([OH:20])([OH:3])=[O:2].[CH3:7][CH2:6][CH2:5][CH:4]([Na:23])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86612902HCID 86612902, compound

Product 1

HCID 178443202HCID 178443202, compoundYield 93.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-Hexadecanyl phosphate (3.13 g, 0.0097 mol) was dissolved in ethanol (150 ml). NaOH (0.37 g, 0.0092 mol) was added and the mixture was stirred for 48 hrs and then evaporated. Ethanol (2×150 ml) was added and evaporated. Ether (2×100 ml) was added and evaporated. The obtained solid was triturated with acetone (100 ml) and dried under 1 mm. Hg atmosphere overnight. 2.98 g of final product was obtained. Yield 87%.

Workup

  1. customevaporated
  2. additionEthanol (2×150 ml) was added
  3. customevaporated
  4. additionEther (2×100 ml) was added
  5. customevaporated
  6. customThe obtained solid was triturated with acetone (100 ml)
  7. customdried under 1 mm. Hg atmosphere overnight

Sources & evidence

ORD record
ord-cb7d17c6738a4db4a3bbfeb45f270955
Source dataset
uspto-grants-2007_03
Patent number
US07186703B2

Reaction notes

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