Dimethylamine → 3-(2-Hydroxyphenyl)-1,1-dimethylurea

HRID 456399Notes

Reaction equation

HRID 456399 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[OH:13])=[O:5])C.N(C1C=CC=CC=1OC)=[C:15]=O.CNC>>[OH:13][C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[NH:6][C:4](=[O:5])[N:3]([CH3:15])[CH3:1]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 69695Benzene, 1-isocyanato-2-methoxy-HCID 18006604HCID 18006604, compound

Product 1

HCID 30194473-(2-Hydroxyphenyl)-1,1-dimethylureaYield 54%

Procedure

The subtitled compound was prepared using the procedure as described for Example 25 for N-ethyl-N′-(2-hydroxyphenyl)urea from 1-isocyanato-2-methoxybenzene and dimethylamine (2M solution in THF). Yield 54%.

Sources & evidence

ORD record
ord-247eb979cb984156839a1b613e26b8cd
Source dataset
uspto-grants-2007_03
Patent number
US07186718B2

Reaction notes

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