反应详情

A mixture of 2-nitro-1,3-benzenediol (1.55 g 10 mmol), acetic anhydride (1.59 g, 1.47 mL, 15 mmol) and 10% palladium on charcoal (0.3 g) in methanol (100 mL) was stirred in the atmosphere of hydrogen at atmospheric pressure for 2 h. The catalyst was filtered through celite, the solvent evaporated in vacuo. The oily residue was treated with dichloromethane to afford colourless crystals, which were collected by filteration and dried to give the subtitle compound (1.09 g, 65%).

1. filtrationThe catalyst was filtered through celite
2. customthe solvent evaporated in vacuo
3. additionThe oily residue was treated with dichloromethane
4. customto afford colourless crystals, which
5. customwere collected by filteration
6. customdried