4,4'-Difluorobenzophenone → HCID 24886803, compound

HRID 456420Notes

Reaction equation

HRID 456420 reaction equation
F[C:2]1[CH:3]=[C:4]([C:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:20])[CH:5]=[C:6](F)[C:7]=1[N:8]1[CH2:13][CH2:12][N:11]2[CH2:14][CH2:15][CH2:16][CH2:17][C@@H:10]2[CH2:9]1.[F:27]C1C=CC(C(C2C=CC(F)=CC=2)=O)=CC=1>>[F:27][C:24]1[CH:23]=[CH:22][C:21]([C:19]([C:4]2[CH:5]=[CH:6][C:7]([N:8]3[CH2:13][CH2:12][N:11]4[CH2:14][CH2:15][CH2:16][CH2:17][C@@H:10]4[CH2:9]3)=[CH:2][CH:3]=2)=[O:20])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 95824,4'-DifluorobenzophenoneHCID 24886802HCID 24886802, compound

Product 1

HCID 24886803HCID 24886803, compound

Procedure

340 mg of the title compound were prepared as described for [3,5-difluoro-4-((R)-octahydropyrido[1,2-a]pyrazin-2-yl)phenyl]-[phenyl]methanone, using 4,4′-difluorobenzophenone instead of 3,4,5-trifluorobenzophenone.

Sources & evidence

ORD record
ord-9eeeec5354f44c5ca51222559995e168
Source dataset
uspto-grants-2007_03
Patent number
US07186721B2

Reaction notes

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