Tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylate → HCID 69421035, compound

HRID 456445Notes

Reaction equation

HRID 456445 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[OH:20])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:21][S:22]([N:25]1[CH2:30][CH2:29][CH2:28][CH:27](O)[CH2:26]1)(=[O:24])=[O:23]>>[C:1]([O:5][C:6]([N:8]1[CH2:9][CH2:10][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:20][CH:27]2[CH2:28][CH2:29][CH2:30][N:25]([S:22]([CH3:21])(=[O:24])=[O:23])[CH2:26]2)[CH2:12][CH2:13]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 11543684Tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylateHCID 179180311-(Methanesulfonyl)piperidin-3-ol

Product 1

HCID 69421035HCID 69421035, compound

Procedure

The title compound was prepared by using Mitsunobu condition from 4-(2-Hydroxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and 1-methanesulfonyl-piperidin-3-ol.

Sources & evidence

ORD record
ord-3138b4cc97ec401f9e34633e2448855b
Source dataset
uspto-grants-2007_03
Patent number
US07186715B2

Reaction notes

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