HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylate → 4-[2-(1-Acetyl-piperidin-3-yloxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylate | HCID 11543684 | — |
| Reactant | 1-(3-Hydroxypiperidin-1-yl)ethan-1-one | HCID 21897030 | — |
| Product | 4-[2-(1-Acetyl-piperidin-3-yloxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 69419750 | — |
Reaction Steps
The title compound was prepared by using mitsonobu condition from 4-(2-hydroxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and 1-(3-Hydroxy-piperidin-1-yl)-ethanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07186715B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-d21bdad073b941cf8053099b071ddabc |
| Source note | uspto-grants-2007_03 |