Hexahydro-1,4-diazepine → HCID 18436723, compound

HRID 456474Notes

Reaction equation

HRID 456474 reaction equation
Br[C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][N:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1.[NH:17]1[CH2:23][CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[N:7]1([CH2:6][CH2:5][O:4][C:3]2[CH:13]=[CH:14][CH:15]=[CH:16][C:2]=2[N:17]2[CH2:23][CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 8672134-[2-(2-bromophenoxy)ethyl]morpholine

Product 1

HCID 18436723HCID 18436723, compound

Procedure

The title compound was prepared in a manner similar to Preparation 63A except that 4-[2-(2-bromo-phenoxy)-ethyl]morpholine was coupled to homopiperazine.

Sources & evidence

ORD record
ord-27cb385001aa48e8b5d36821b6b8b94b
Source dataset
uspto-grants-2007_03
Patent number
US07186715B2

Reaction notes

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