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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456519Generated: October 25, 2026

1-(3-Chlorophenyl)piperazine monohydrochloride → HCID 178455806, compound

https://huagongshe.com/reaction/456519

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chlorophenyl)piperazine monohydrochlorideHCID 25681—
Reactant1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine hydrochlorideHCID 16245490—
ReactantHCID 178455808HCID 178455808—
ProductHCID 178455806HCID 178455806—

Reaction Steps

Follow the procedure of Example 11e, and substitute methane sulfonic acid 2-(trans-4-ethyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester (Example 13d) for 2-(trans-4-methyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester and 4-(3-chloro-5-trifluoromethyl-pyridin-2-yl)-piperazine hydrochloride for 1-(3-chloro-phenyl)-piperazine hydrochloride therein to obtain the title compound LC/MS m/z=473 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07186724B2
Source datasetuspto-grants-2007_03
ORD IDord-e5f8525c4043468b89f0463768df4bde
Source noteuspto-grants-2007_03