関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4-Bromophenacyl bromide | HCID 7454 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Benzenemethanamine, 2,4-dichloro-N-methyl- | HCID 485424 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 1-(4-Bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone | HCID 22386828 | — |
反応手順
Into a 250-mL 3-necked round-bottom flask purged and maintained with an inert atmosphere of nitrogen, was placed a solution of 2-bromo-1-(4-bromophenyl)ethanone (9.3 g, 33.45 mmol, 1.00 equiv) in dioxane (100 mL), triethylamine (5.0 g, 1.50 equiv), and (2,4-dichlorophenyl)-N-methylmethanamine (6.4 g, 33.68 mmol, 1.00 equiv). The resulting solution was stirred for 2 h at 25° C. The solids were filtered out. The filtrate was used for next step directly.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08541448B2 |
|---|
| 出典データセット | uspto-grants-2013_09 |
|---|
| ORD ID | ord-bcbc59806f7f4a2abcfb0732df48476e |
|---|
| 出典メモ | uspto-grants-2013_09 |
|---|
