Sodium Iodide → 6-(2-Iodo-ethyl)-2,3-dihydro-benzo[1,4]dioxine

Participants

Reaction Steps

A solution of (a) (0.22 g) in acetone (10 ml) was treated with sodium iodide (0.6 g) and heated to reflux overnight. The mixture was filtered and evaporated. The residue was partitioned between dichloromethane and dilute aqueous sodium sulphite solution. The organic extract was dried and evaporated to give a brown oil (0.25 g).

Provenance & Evidence