HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456663Generated: October 30, 2026
Hydrazine hydrate (1:1) → HCID 178522050, compound
https://huagongshe.com/reaction/456663
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 5-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-2-carboxylic acid (3-fluoro-phenyl)-amide | HCID 86592244 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178522050 | HCID 178522050 | 45% |
Reaction Steps
A mixture of 5-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-2-carboxylic acid (3-fluoro-phenyl)-amide (477 mg, 1.4 mmol) and hydrazine hydrate (2 mL) in ethanol (30 mL) was heated at 80° C. for 24 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 200 mg (45%) of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07186716B2 |
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| Source dataset | uspto-grants-2007_03 |
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| ORD ID | ord-e6d59d8f378c42709b1c9ec546f7211d |
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| Source note | uspto-grants-2007_03 |
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