HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456668Generated: October 30, 2026
Hydrazine hydrate (1:1) → HCID 178469881, compound
https://huagongshe.com/reaction/456668
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 4-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 86592247 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178469881 | HCID 178469881 | 16.3% |
Reaction Steps
A mixture of 4-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-3-carboxylic acid ethyl ester (170 mg, 0.6 mmol) and hydrazine hydrate (0.8 g) in ethanol (10 mL) was heated at 80° C. for 24 hours. The reaction was concentrated, the residue was recrystallized to give 25 mg (16%) of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07186716B2 |
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| Source dataset | uspto-grants-2007_03 |
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| ORD ID | ord-a04d752472284ca18ed1c60d2341bc2e |
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| Source note | uspto-grants-2007_03 |
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