Oxalyl chloride → HCID 86592252, compound

Participants

Reaction Steps

5-(2-Chloro-5-nitro-benzoyl)-1H-pyrrole-2-carboxylic acid (200 mg) was converted to 5-(2-chloro-5-nitro-benzoyl)-1H-pyrrole-2-carbonyl chloride using oxalyl chloride at room temperature for one hour. It was then condensed with 2-morpholin-4-yl-ethylamine and TEA for one hour at room temperature to give 120 mg of 5-(2-chloro-5-nitro-benzoyl)-1H-pyrrole-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide.

Provenance & Evidence