HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenol → HCID 86592253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 18436887 | HCID 18436887 | — |
| Reactant | HCID 18436888 | HCID 18436888 | — |
| Product | HCID 86592253 | HCID 86592253 | 51.6% |
Reaction Steps
5-(2-Chloro-5-nitro-benzoyl)-1H-pyrrole-2-carboxylic acid (200 mg) (Example 63) was converted to 5-(2-chloro-5-nitro-benzoyl)-1H-pyrrole-2-carbonyl chloride using oxalyl chloride at room temperature for one hour. It was then condensed with 3-amino-phenol (170 mg, 1.7 eq.) and TEA at room temperature for 1.5 hrs to give 135 mg of 5-(2-chloro-5-nitro-benzoyl)-1H-pyrrole-2-carboxylic acid (3-hydroxy-phenyl)-amide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07186716B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-0c38ce56c7084cafad47b28f06e3a7a8 |
| Source note | uspto-grants-2007_03 |