HCID 58625199, compound → HCID 178519213, compound

Participants

Reaction Conditions

Reaction Steps

(5R)-3-{3-Fluoro-4-[1-(4-methoxybenzyl)-1H-1,2,3-triazol-4-yl]phenyl}-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one (Intermediate 15, 1.12 g, 2.49 mnol) was dissolved in trifluoroacetic acid (20 ml) and stirred at 65° C. overnight. The solution was concentrated then diluted with water until a precipitate formed. The light green solid was recrystallized using acetone and methanol to give the desired product as a beige solid (0.782 g).

Provenance & Evidence