Cesium carbonate → {[6-(5-Phenyl-1H-pyrrol-2-yl)-2-naphthyl]oxy}acetonitrile

Participants

Reaction Steps

In a similar manner as described in step 6 of Example 1, the title compound was prepared from 6-(5-phenyl-1H-pyrrol-2-yl)-2-naphthol (0.285 g, 1.00 mmol), prepared in step 5 of Example 1, bromoacetonitrile (0.144 g, 1.20 mmol) and cesium carbonate (1.63 g, 5.00 mmol) with the exception that the reaction was complete after 2 hours at ambient temperature. The isolated tan solids (0.323 g, 100%) were used without further purification, mp 141.5–142.5° C. Elemental Analysis for C22H16N2O Calc'd: C, 81.46; H, 4.97; N, 8.64. Found: C, 80.37; H, 4.93; N,

Provenance & Evidence